Shape from shading with interreflections under proximal light source - 3D shape reconstruction of unfolded book surface from a scanner image

We address the problem to recover the 3D shape of an unfolded book surface from the shading information in a scanner image. From a technical point of view, this shape from shading problem in real world environments is characterized by (1) proximal light source, (2) interreflections, (3) moving light source, (4) specular reflection, and (5) nonuniform albedo distribution. Taking all these factors into account, we first formulate the problem based on an iterative nonlinear optimization scheme. Then we introduce piecewise polynomial models of the 3D shape. Image restoration experiments for a real book surface demonstrated that geometric and photometric distortions are almost completely removed by the proposed method</p

Colonic Paneth cell metaplasia is pre-neoplastic condition of colonic cancer or not?

BACKGROUND: The carcinogenesis of colorectal cancer has been accepted by a model for a cascade of genetic alterations, named the adenoma-carcinoma sequence. In order to elucidate the carcinogenesis of the colorectal cancer more clearly, the genetic abnormalies of the non-neoplastic mucosal epithelium of the colon and rectum should be investigated. It has been speculated that colonic Paneth cell metaplasia (PaM) is one of the pre-neoplastic mucosa of colonic cancer. Therefore, we studied the propria mucosa of the right colon with PaM from the standpoints of the frequency of the K-ras codon 12 mutations (K-ras), which is initial genetic abnormality in colorectal cancer, and the loss of heterozygosity of microsatellite markers (LOH-MS), which has a relationship to development of colorectal cancer. METHODS: Fifty-two regions with PaM histopathologically from 12 surgically resected right colon specimens were studied. DNA extraction of the colonic mucosa with PaM was obtained using a microdissection method, and the frequency of the K-ras of PaM was investigated by enriched polymerase chain reaction-enzyme linked mini-sequence assay, and the frequency of the LOH-MS (D2S123, D17S250 and D5S346) of PaM was examined by high resolution fluorescenced labeled PCR primers. RESULTS: K-ras mutation was detected in fifteen regions among 52 PaM (28.9%). All mutations were a single mutation and GGT changed to AGT in eleven and GAT in four. LOH-MS were detected in twenty-one regions among 52 PaM (40.4%) (D2S123: 35.4%, 17/48 regions, D17S250: 13.7%, 7/51 regions, and D5S346: 0%, 0/52 regions). No K-ras mutations and LOH-MS were detected in the controls (Colorectal mucosa with no PaM). CONCLUSIONS: Colonic mucosa with Paneth cell metaplasia may be one of the pre-neoplastic mucosa in the development of the colonic epithelial neoplasia

Appearance sphere: background model for pan-tilt-zoom camera

Background subtraction is a simple and effective method to detect anomalous regions in images. In spite of the effectiveness, it cannot be used with an active (moving) camera head because the background image varies with camera-parameter control. This paper presents a background subtraction method with pan-tilt-zoom control. The proposed method consists of an omnidirectional background model called appearance sphere and parallax free sensing. Based on this model, precise background images can be generated and background subtraction can be performed for any combination of pan-tilt-zoom parameters without restoring 3D scene information</p

&#947;-&#969; Hough transform-elimination of quantization noise and linearization of voting curves in the &#961;-&thetas; parameter space.

It is known that the &#961;-&#952; parameter space has inherent bias, and it has been treated as the appearance of the white noise in the image space. In this paper, the authors first show that the bias is caused by the uniform quantization of the parameter space. To eliminate the bias, a new parameter &#947; representing a nonuniform quantization along the &#961;-axis is introduced and the &#947;-&#952; parameter space is constructed. In this space, the uniform quantization does not introduce any bias. Then, by a nonlinear transformation of &#952;, the &#947;-&#969; parameter space is derived, in which a voting curve becomes a pair of straight lines preserving the unbiasedness</p

Probing a ferromagnetic critical regime using nonlinear susceptibility

The second order para-ferromagnetic phase transition in a series of amorphous alloys (Fe{_5}Co{_{50}}Ni{_{17-x}}Cr{_x}B{_{16}}Si{_{12}}) is investigated using nonlinear susceptibility. A simple molecular field treatment for the critical region shows that the third order suceptibility (chi{_3}) diverges on both sides of the transition temperature, and changes sign at T{_C}. This critical behaviour is observed experimentally in this series of amorphous ferromagnets, and the related assymptotic critical exponents are calculated. It is shown that using the proper scaling equations, all the exponents necessary for a complete characterization of the phase transition can be determined using linear and nonlinear susceptiblity measurements alone. Using meticulous nonlinear susceptibility measurements, it is shown that at times chi{_3} can be more sensitive than the linear susceptibility (chi{_1}) in unravelling the magnetism of ferromagnetic spin systems. A new technique for accurately determining T{_C} is discussed, which makes use of the functional form of chi{_3} in the critical region.Comment: 11 Figures, Submitted to Physical Review

Feedback Control of the Arachidonate Cascade in Osteoblastic Cells by 15-deoxy-Δ12,14-Prostaglandin J2

15-deoxy-Δ12,14-prostaglandin J2 (15d-PGJ2) and an anti-diabetic thiazolidinedione, troglitazone (TRO) are peroxisome proliferator-activated receptor (PPAR)-γ ligands, which regulate immuno-inflammatory reactions as well as adipocyte differentiation. We previously reported that 15d-PGJ2 can suppress interleukin (IL)-1β-induced prostaglandin E2 (PGE2) synthesis in synoviocytes of rheumatoid arthritis (RA). IL-1 also stimulates PGE2 synthesis in osteoblasts by regulation of cyclooxygenase (COX)-2 and regulates osteoclastic bone resorption in various diseases such as RA and osteoporosis. In this study, we investigated the feedback mechanism of the arachidonate cascade in mouse osteoblastic cells, MC3T3-E1 cells, which differentiate into mature osteoblasts. Treatment with 15d-PGJ2 led to a significant increase in IL-1α-induced COX-2 expression and PGE2 production in a dose dependent manner. The effect of 15d-PGJ2 was stronger than that of TRO. However, it did not affect the expression of COX-1. In addition, cell viability of MC3T3-E1 cells was not changed in the condition we established. This means that 15d-PGJ2 exerts a positive feedback regulation of the arachidonate cascade of PGE2 in osteoblastic cells. These results may provide important information about the pathogenesis and treatment of bone resorption in a variety of diseases such as RA and osteoporosis